What is the appropriate dosing of Diphenhydramine for a patient weighing equal to or less than 25kg?

Diphenhydramine, an antihistamine used for various allergic reactions and conditions, has a recommended dosage that considers the patient's weight, particularly in pediatric patients. For a patient weighing 25 kg or less, the appropriate dosing guideline is typically 1 mg/kg, with a maximum single dose often capped at 25 mg. Therefore, for a patient of this weight, a dose of 25 mg would be within the recommended dosing range and would effectively provide therapeutic benefit while minimizing the risk of overdose.

Choosing 25 mg fits within the established safety guidelines for this medication, balancing efficacy with safety, especially in a primary care setting. Doses above this (such as 50 mg, 100 mg) may lead to increased risk of side effects, particularly in younger patients, who may be more sensitive to medications. A lower dose, like 10 mg, would not provide adequate therapeutic effect for this patient's weight, as it would fall below the maximum dose established by guidelines for effective treatment.