Which of the following is a contraindication for administering Ibuprofen?

Administering Ibuprofen during pregnancy is contraindicated due to potential risks to both the mother and her developing fetus. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as Ibuprofen, can affect fetal development, particularly during the third trimester, where they may lead to issues such as fetal renal dysfunction, oligohydramnios, and potential complications during delivery. Healthcare providers typically recommend alternatives like Acetaminophen for pain relief in pregnant individuals because it is generally considered safer during pregnancy, especially when addressing mild to moderate discomfort.

The other options do not pose the same level of risk or contraindication for Ibuprofen use. Previous use of Acetaminophen does not impact the safety or efficacy of Ibuprofen. A history of mild headaches suggests a potential need for pain management rather than a contraindication. Unaltered mental status does not indicate any inherent risk or contraindication for using Ibuprofen, as it pertains more to the patient's consciousness and cognitive function rather than to the medication's safety profile.