What route is used for administering Glucagon to a patient less than 25kg?

When administering Glucagon to a patient who weighs less than 25 kg, the intramuscular (IM) route is the preferred method. This is because IM injections allow for effective absorption of the medication into the bloodstream, providing a rapid response in the case of severe hypoglycemia.

Glucagon works by stimulating glycogenolysis in the liver, rapidly increasing blood glucose levels. Administering it intramuscularly ensures that it can work effectively, especially in emergency situations. It is also important to note that Glucagon is typically provided in a prefilled syringe or as a powder that needs to be reconstituted, and IM administration is straightforward and quick in an emergency setting.

Other routes such as intravenous (IV) or subcutaneous (subcut) are less commonly used for Glucagon, particularly in pediatric patients under 25 kg due to the challenges in establishing IV access in emergencies. Additionally, the oral route is not viable for Glucagon administration as it requires injection to bypass the digestive system for effective action.