What is the maximum time frame to transport a patient to a Designated Stroke Centre if Endovascular Therapy is not available?

Transporting a patient experiencing a stroke to a Designated Stroke Centre within the appropriate time frame is crucial for effective treatment and improved outcomes. The maximum time frame of 4.5 hours from the onset of symptoms is supported by guidelines from health authorities and stroke management protocols. This timeframe aligns with the window for administering alteplase (tPA), a thrombolytic therapy which can significantly reduce the morbidity and mortality associated with ischemic strokes when given promptly.

In clinical practice, time is often referred to as "brain," emphasizing the urgency of restoring blood flow to minimize brain damage. Beyond 4.5 hours, the risks associated with thrombolysis may outweigh the potential benefits, indicating a shift in treatment options might be required.

Receiving treatment within this 4.5-hour window maximizes the chance for recovery and minimizes long-term complications, underscoring the importance of timely transport to a facility equipped to provide advanced care.